2010. For more information see this CDC website:
CDC Lyme disease cases
Iowans and anyone else interested in discussing Lyme issues.
Want to find out how others are being treated? Is someone else
afflicted with the same symptom? You are not alone, dealing with
this disease. Let's help each other!
Iowa Lyme Group on Facebook
a good time to educate Iowan's. Contact us for more information.
for a friend in UK or another state? Does your local physician need
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|***Disclaimer: The information provided on this web site should not take
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National - State - Midwest
|Iowa lyme Disease Association - Education
P.O. Box 221
Brighton, IA 52540
Email: [email protected]
Ticks are active
with all of the
rainfall. Be sure
pants and long
and check every
so often for
on your clothes.
not let outdoor
and dry in a high
heat cycle for at
least 30 min. to
and the bacteria.
|Letter from Dr. Burrascano
September 5, 2011 Joe Burrascano, Jr., MD has
announced a new lab test available for Lyme doctors to
use in determining if Lyme is present. There is no need
to wait for antibodies to form since this is a culture-based
test. This should provide much faster and more accurate
detection, and allow Lyme patients to receive treatment
as soon as possible. Please read below for Dr.
Burrascano's description of the new test:
In my work as a consultant, I have been working with
a private lab located near Philadelphia, Advanced
Laboratories, Inc. They wanted to develop a unique and
high value test, and, with my interest in Lyme, I naturally
encouraged them to work on a better Lyme Disease test.
As a result of some very intensive work on the part
of a group of some very brilliant scientists, they have
succeeded in developing a reliable and rapid blood
culture for Borrelia!
They actually have rolled out two separate panels-
a basic one and an advanced one. In the basic panel,
the blood sample is cultured and the positives are
identified by histology and growth characteristics, and
confirmed by fluorescent immunostaining.
Positive reports will include a picture of the Bb growing in
that very culture.
The advanced panel will do this, but will also do
PCR using well characterized and published DNA primer
sets, and then all positive PCRs will be confirmed by DNA
Remarkably, turn-around time can be as brief as
ten days for the basic test, and seven to ten more days
for the advanced panel.
The next step in their research is also equally
exciting and ground breaking, but I am not at liberty to
say yet what is being planned.
As many of you recall, I learned the basics of true,
clinical Lyme over 25 years ago thanks to Bb culturing
that was available to me by Dr. Alan MacDonald. The
new methods being used by this Pennsylvania lab go far
beyond what MacDonald was able to do, so I am very
excited to not only share this news with you, but I also
cannot wait to see how it will change how we practice.
I also predict that Bb will be found in a lot of people,
from mildly to severely ill, and that will redefine the role of
the immunologist in Lyme to find out why some people
recover and why others do not. Strain information as
provided by the DNA sequencing data will be equally
fascinating to follow.
Copyright © 2007 - 2022 Iowa Lyme Disease Association (ILDA).
All Rights Reserved.
Standard in Lyme Disease testing. Lyme Disease blood
testing has been notorious for its unreliability. This has
been responsible for misdiagnoses and inappropriate
patient care, as well as confusion on the part of both
patient and physician alike. Now, as a result of intensive
research, Advanced Laboratory Services Inc. is able to
offer what will rapidly become the new gold standard of
Lyme tests, the Borrelia Culture.
Until now, the most widely used confirmatory tests for
Lyme disease have been serologies, such as the ELISA
and the Western Blot. Being indirect tests, at best they
can only indicate possible exposure to this organism at
some previous point in time. The sensitivity of these
assays is low and may miss anywhere from 30% to as
many as 70% of cases of Lyme. Once positive, these
serologic tests tend to remain positive for variable
periods, even years, even after treatment. Therefore they
do not and cannot be used as a marker for progress
during treatment or for success of treatment.
While still considered investigational, this new
method of testing for Lyme allow these advantages:
Currently, Advanced Labs is offering two Borrelia
blood culture panels: *
1. The Basic Panel consists of culturing, with confirmation
of identity by histology and by specific immunostaining.
The report will include a picture of the actual
immunostained culture result. This panel will take
approximately ten to fourteen days. However, some do
grow more slowly, so all cultures will be held in the lab for
a minimum of six weeks.
2. The Extended Panel will include all of the above, plus
the identity of all positive cultures will be further studied by
polymerase chain reaction (PCR) and by nucleic acid
sequencing. These extra steps will require an additional
ten to fourteen days. However, if the initial histology with
immunostaining is positive, a preliminary report will be
issued while the nucleic acid studies are pending.
* Costs for the tests will be in the range of under
$500 for the basic test; the extended culture tests will be
approximately $200 more. Also, testing must be paid for in
advance, but patients may submit their paid receipt to
their own insurance carriers for reimbursement.
Bb culture nuts and bolts:
- If the patient is symptomatic at the time of blood
draw and not on antibiotics for at least four weeks, the
test sensitivity exceeds 80%.
- All negative controls have remained negative, so
- As with all blood cultures, the patient may need
several sets to be sure.
- Any positive test is significant, even if it is the only
positive out of a set of three.
The success of culturing Borrelia can be increased
by following these simple recommendations:
1. The patient should not have been exposed to any
antibiotics, for a minimum of four weeks prior to the blood
sample being drawn.
2. Borrelia are more likely to be recovered from patients
who are symptomatic at the time of blood sampling.
3. A higher yield may be seen if the blood is drawn in the
early afternoon, when most infected patients feel
Contact the lab to have test kits sent to you or your
local physician. The blood must be sent out the same day
it is collected, and the lab provides a prepaid return
FedEx mailer. As the lab is not yet accepting specimens
over weekends, please do not collect blood on Fridays.
For more information contact:
Advanced Laboratory Services, Inc. 501 Elmwood
Sharon Hill, PA 19079
E-mail: [email protected]
Toll Free Phone: 855-238-4949, Fax: 855-238-4946